Anti-Signal Recognition Particle Myopathy in a Geriatric Patient
نویسندگان
چکیده
منابع مشابه
Immune-mediated Necrotizing Myopathy With Increased Creatine Phosphokinase and Positive Signal Recognition Particle: A Case Report
Background: Knowledge about Immune-Mediated Necrotizing Myopathy (IMNM) has received significantly attention in recent years. In this study, we report a rare case of IMNM with increased Creatine Phosphokinase (CPK) and positive Signal Recognition Particle (SRP). Clinical Presentation and Intervention: The case was a 67-year-old male patient referred to Firozgar hospital affiliated to the Iran ...
متن کاملAnti-signal recognition particle autoantibody in patients with and patients without idiopathic inflammatory myopathy.
OBJECTIVE To determine the long-term outcome and associated clinical, serologic, and pathologic features in a cohort of patients with connective tissue disease (CTD) and the anti-signal recognition particle (anti-SRP) autoantibody. METHODS Sera and clinical data were collected prospectively from consecutive adult patients with polymyositis (PM; n = 134), dermatomyositis (n = 129), or other CT...
متن کاملInflammatory myopathy with anti-signal recognition particle antibodies: case series of 100 patients
BACKGROUND Anti-signal recognition particle (SRP) antibodies are used as serological markers of necrotizing myopathy, which is characterized by many necrotic and regenerative muscle fibers without or with minimal inflammatory cell infiltration. The clinical spectrum associated with anti-SRP antibodies seems to be broad. OBJECTIVE To describe the clinical characteristics, autoantibodies status...
متن کاملGastric Strongyloides Stercoralis in a Patient with Inflammatory Myopathy
Strongyloides stercoralis is a free living tropical and semitropical soil nematode which its larva penetrates skin. It can complete its life cycle in human body and causes autoinfection. Most patients have no frank symptoms. But respiratory, gastrointestinal and skin manifestation may occur. We report a 76 year old man admitted to emergency room with muscle weakness, dyspnea, nausea, v...
متن کاملAnti-signal recognition particle autoantibody ELISA validation and clinical associations.
OBJECTIVE The aim of this study was to develop and validate a quantitative anti-signal recognition particle (SRP) autoantibody serum ELISA in patients with myositis and longitudinal association with myositis disease activity. METHODS We developed a serum ELISA using recombinant purified full-length human SRP coated on ELISA plates and a secondary antibody that bound human IgG to detect anti-S...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Case Reports in Internal Medicine
سال: 2015
ISSN: 2284-2594
DOI: 10.12890/2015_000311